Mutations in Fallout 76 are essentially what you use to get perks, buffs and even more. The perks have both negative and positive effects, which are known as insertion and deletion. This brings an interesting dynamic to the Fallout 76 game where you’ll have to consider both the positive and negative impact of your player before you use a Mutation.
For example, the Herbivore Mutation will grant you double stats when eating plants but prevent you from getting any benefits from eating meat. There are a lot of these in Fallout 76, each with its own set of deletion and insertion effects. In this guide, we will walk you through how to get mutations in Fallout 76. But if you’re looking for a head start, consider checking out Fallout 76 items for sale to kickstart your gameplay and save time gathering resources.
How to Get Mutations in Fallout 76

Mutations can be obtained by randomly walking through spots of radiation on the Fallout 76 map. This can happen literally anywhere ranging from spots that have been nuked, or if you take damage from irradiated creatures. It’s also important to note that you won’t be able to get mutation from radiation until you’re level 5.
The Best Way to Farm Mutations in Fallout 76
While there can be several ways of farming mutations, we believe the best method is by entering the Emmett Mountain Random Disposal Site. Beneath there is a radioactive pool at the very base of the Disposal Site. Once you enter the pool, you’ll be granted several mutations, some of which you’ll have to rinse off in the Contamination Shower.
Lastly, use the Starched Genes Perk Card to grant yourself the Mutations Fallout 76 that you do actually want. It’s recommended to have this at the max level to get the best effect and obtain exactly the Mutations Fallout 76 that you plan on getting.
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All Mutations in Fallout 76

Now we will be taking a look at all the different mutations you can obtain in Fallout 76. All mutations have a corresponding insertion and deletion ability, which we will be noting down in the list below.
- Unstable Isotope
- Insertion: Chance to create a radiation blast when hit by melee attacks
- Deletion: Inflicts small DMG to the player during the blast
- Twisted Muscles
- Insertion: +25% Melee DMG and better cripple limbs
- Deletion: 50% gun accuracy
- Talons
- Insertion: Fist deals +25% normal and bleed damage
- Deletion: Deducts four Agility points
- Speed Demon
- Insertion: +20% movement and reload speed
- Deletion: +50% hunger and thirst drain
- Scaly Skin
- Insertion: +50 Damage and Energy Resistance
- Deletion: -50 Action Points
- Plague Walker
- Insertion: Poison aura scaling with diseases
- Deletion: Works only when there’s a disease
- Marsupial
- Insertion: Increases carry weight (+20) and jump height
- Deletion: Deducts four Intelligence points
- Herbivore
- Insertion: Eating plants grants double stats
- Deletion: Eating meat does not grant additional stats
- Healing Factors
- Insertion: +300% Health Regeneration in non-combat situations
- Deletion: 55% Chem Effects
- Grounded
- Insertion: +100 Energy Resistance
- Deletion: -50% Energy DMG
- Empath
- Insertion: 25% less DMG to teammates
- Deletion: 33% more DMG to the player
- Electrically Charged
- Insertion: Melee attackers might get shocked
- Deletion: Shocks deal some DMG to the player
- Egg Head
- Insertion: Gives six extra Intelligence points
- Deletion: Reduces Strength and Endurance by three points each
- Eagle Eyes
- Insertion: Give four Perception points and increase Critical Hit chance by 60%
- Deletion: Deducts four Strength points
- Chameleon
- Insertion: Grants invisibility
- Deletion: Works only when the player is unarmed and is standing still
- Carnivore:
- Insertion: Eating meat grants double stats
- Deletion: Eating plants does not grant additional stats
- Bird Bones
- Insertion: Increases Agility by four points
- Deletion: Decreases Strength by four points
- Adrenaline Reaction:
- Insertion: Extra weapon damage when HP is low
- Deletion: Deduct 50 points from max HP
- Hard mentality
- Insertion: +2 to SPECIAL stats when grouped
- Deletion: -2 to SPECIAL stats when solo

As you can see, each of them have very unique points which you can use to create a plethora of builds, which is the main attraction of RPG games like Fallout 76. You can get very aggressive mutations that increase your attack and increase your overall stats but at the same time, you have to be cognizant about the deletion perks you’re getting with the mutations. This applies for all mutation builds, of course.
Of course, there are mutations that are simply better or worse than some, and you’ll definitely want to keep an eye out on the best Fallout 76 mutations. That’s what we’ll be taking a look at now.
The Best Mutations to Use in Fallout 76

There are 20 Mutations available in Fallout 76, all available to farm from the spot we’ve mentioned above, or obtainable randomly from radiation sources in the game. But the best mutations you should try and farm are:
- Adrenaline Reaction – The extra damage when your HP is low is definitely worth the push you need when things get a little bit chaotic.
- Scaly Skin – You get extra damage points and energy resistance from getting this mutation, which is reason enough for you to farm this as soon as possible. The lack of 50 action points is hardly a nuisance considering the benefits this mutation gives you.
- Marsupial – Three words: “Increased jump height”. Not to mention, who doesn’t like extra weight capacity in survival games like Fallout?
- Speed Demon – The increased reload speed and movement is 100% worth the extra thirst and hunger you’ll get from acquiring this mutation.
How to Remove Mutations in Fallout 76
If you don’t like a particular mutation in Fallout 76, the quickest way to get rid of them is by drinking RadAway Serums. Not only that, you can also take a quick Decontamination Shower to rid yourself of Fallout 76 mutations quite easily. Other options include consuming Nuka-Grape or Brahmin Milk.

That concludes everything about mutations, including how you can obtain them, the best methods for doing so and also the best mutations that you can use on your Fallout 76 character. You can experiment quite a lot with this feature and see for yourself what works best. That’s the beauty of an RPG game like Fallout 76! We hope this article helps you in understanding how mutations work and that it helps you fine-tune your characters to make the best out of an incredible game like Fallout 76.